BDBM435709 (2R,3S,4R,5R)-3-methyl-5-(4-methyl-7H- pyrrolo[2,3-d]pyrimidin-7-yl)-2-(((3- methylimidazo[1,2-a]pyridin-7- yl)oxy)methyl)tetrahydrofuran-3,4-diol::US10570140, Example 67::US11078205, Example 67::US11208416, Example 67
SMILES Cc1cnc2cc(OC[C@H]3O[C@H]([C@H](O)[C@]3(C)O)n3ccc4c(C)ncnc34)ccn12
InChI Key InChIKey=HADKMWKTGHTOQQ-XRULBBBTSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 435709
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics
US Patent
Prelude Therapeutics
US Patent
Affinity DataIC50: 1nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics
US Patent
Prelude Therapeutics
US Patent
Affinity DataIC50: 1nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair