BDBM495257 1-(3-Fluoro-4-(trifluoromethyl)benzyl)-4-(5-morpholino-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2(1H)-one::US10995089, Example 230::US11708364, Example 230

SMILES Fc1cc(Cn2ccc(cc2=O)-c2c[nH]c3ncc(cc23)N2CCOCC2)ccc1C(F)(F)F

InChI Key InChIKey=KGEKBWFMBQUJPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 495257   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Agv Discovery

US Patent
LigandPNGBDBM495257(1-(3-Fluoro-4-(trifluoromethyl)benzyl)-4-(5-morpho...)
Affinity DataIC50: <10nMAssay Description:To assess compounds capacity to inhibit ERK2 enzymatic activity, Z′-Lyte biochemical assay from Life technologies was used according to manufac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Agv Discovery

US Patent
LigandPNGBDBM495257(1-(3-Fluoro-4-(trifluoromethyl)benzyl)-4-(5-morpho...)
Affinity DataIC50: <150nMAssay Description:To assess compounds capacity to inhibit ERK2 enzymatic activity, Z′-Lyte biochemical assay from Life technologies was used according to manufac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent