BDBM50000541 (+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea::1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea::CHEMBL93::Leutrol::N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea::N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea::ZILEUTON::Zyflo (TN)
SMILES CC(N(O)C(N)=O)c1cc2ccccc2s1
InChI Key InChIKey=MWLSOWXNZPKENC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50000541
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Ferrara
Curated by ChEMBL
University Of Ferrara
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human 5-LOX expressed in Escherichia coli Bl21 (DE3) assessed as reduction in LTB4 and 5-H(P)ETE) formation pre-incubated for 10 mins b...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Ferrara
Curated by ChEMBL
University Of Ferrara
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of 5-LOX in human neutrophils assessed as reduction in LTB4 and 5-H(P)ETE) formation pre-incubated for 15 mins before A23187 and arachidon...More data for this Ligand-Target Pair