BDBM50013808 CHEMBL3265265::US10323013, Compound 25

SMILES Oc1ccc2c3CCN(Cc3c(=O)oc2c1C1SCCCS1)C(=O)OCC=C

InChI Key InChIKey=DWSLMEUOGIKYLG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50013808   

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50013808(CHEMBL3265265 | US10323013, Compound 25)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of human recombinant puritin-His-tagged IRE-1 RNase expressed in SF21 cells using XBP-1 RNA stem loop as substrate incubated for 30 mins p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed