BDBM50048190 CHEMBL289262::N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-indan-5-yl]-methanesulfonamide

SMILES CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1nccs1

InChI Key InChIKey=DXXOQPYKXLLPNU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50048190   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048190(CHEMBL289262 | N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-i...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 activity in U937 microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048190(CHEMBL289262 | N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-i...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048190(CHEMBL289262 | N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-i...)
Affinity DataIC50:  480nMAssay Description:Inhibition of purified recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048190(CHEMBL289262 | N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-i...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2 expressed in CHO (chinese hamster ovary) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048190(CHEMBL289262 | N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-i...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of purified recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048190(CHEMBL289262 | N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-i...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed