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Found 3 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50048190'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048190(CHEMBL289262 | N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-i...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048190(CHEMBL289262 | N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-i...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2 expressed in CHO (chinese hamster ovary) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048190(CHEMBL289262 | N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-i...)
Affinity DataIC50:  480nMAssay Description:Inhibition of purified recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed