BDBM50142515 CHEMBL44747::N-Benzothiazol-2-yl-3,4-dihydroxy-benzamide

SMILES Oc1ccc(cc1O)C(=O)Nc1nc2ccccc2s1

InChI Key InChIKey=GNKKDFRNLWHCEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142515   

TargetDNA topoisomerase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142515(CHEMBL44747 | N-Benzothiazol-2-yl-3,4-dihydroxy-be...)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed