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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 1' and Ligand = 'BDBM50142515'
Target
DNA topoisomerase 1
(Homo sapiens (Human))
Kumamoto University
Curated by
ChEMBL
Ligand
BDBM50142515
(CHEMBL44747 | N-Benzothiazol-2-yl-3,4-dihydroxy-be...)
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Affinity Data
IC50: 1.69E+4nM
Assay Description:
Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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