BDBM50144159 CHEMBL294800::N-(1-Methoxy-6-m-tolyl-6H-benzo[c]chromen-8-yl)-methanesulfonamide

SMILES COc1cccc2OC(c3cccc(C)c3)c3cc(NS(C)(=O)=O)ccc3-c12

InChI Key InChIKey=JRZWVYSKNVMDLP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50144159   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144159(CHEMBL294800 | N-(1-Methoxy-6-m-tolyl-6H-benzo[c]c...)
Affinity DataIC50:  21nMAssay Description:Effect on human Glucocorticoid receptor (GR) in a whole cell assay to measure functional cellular GR-antagonism (GRAF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144159(CHEMBL294800 | N-(1-Methoxy-6-m-tolyl-6H-benzo[c]c...)
Affinity DataIC50:  236nMAssay Description:Displacement of [3H]progesterone from human Progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144159(CHEMBL294800 | N-(1-Methoxy-6-m-tolyl-6H-benzo[c]c...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 70-92 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144159(CHEMBL294800 | N-(1-Methoxy-6-m-tolyl-6H-benzo[c]c...)
Affinity DataIC50:  333nMAssay Description:Displacement of [3H]aldosterone from human Mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144159(CHEMBL294800 | N-(1-Methoxy-6-m-tolyl-6H-benzo[c]c...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]mibolerone from human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed