BDBM50153668 3-[(S)-2-(2,4-Dichloro-benzyloxycarbonylamino)-3-methyl-butyrylamino]-5-fluoro-4-oxo-pentanoic acid::CHEMBL185356

SMILES CC(C)[C@H](NC(=O)OCc1ccc(Cl)cc1Cl)C(=O)NC(CC(O)=O)C(=O)CF

InChI Key InChIKey=ANNPALXBOKTDBF-VYIIXAMBSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50153668   

TargetCaspase-7(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50153668(3-[(S)-2-(2,4-Dichloro-benzyloxycarbonylamino)-3-m...)
Affinity DataIC50:  10nMAssay Description:Inhibition concentration required against caspase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50153668(3-[(S)-2-(2,4-Dichloro-benzyloxycarbonylamino)-3-m...)
Affinity DataIC50:  6nMAssay Description:Inhibition concentration required against caspase-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-9(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50153668(3-[(S)-2-(2,4-Dichloro-benzyloxycarbonylamino)-3-m...)
Affinity DataIC50:  9nMAssay Description:Inhibition concentration required against caspase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50153668(3-[(S)-2-(2,4-Dichloro-benzyloxycarbonylamino)-3-m...)
Affinity DataIC50:  25nMAssay Description:Inhibitory activity against human recombinant caspase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed