BDBM50170758 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)-5-{3-[4-(4-sulfamoyl-benzylsulfamoyl)-phenyl]-thioureido}-benzoic acid::CHEMBL360604

SMILES NS(=O)(=O)c1ccc(CNS(=O)(=O)c2ccc(NC(=S)Nc3ccc(c(c3)C(O)=O)-c3c4ccc(O)cc4oc4cc(=O)ccc34)cc2)cc1

InChI Key InChIKey=XQXLDTMLIZQSJA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50170758   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50170758(2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)-5-{3-[4-(4-sul...)
Affinity DataKi:  20nMAssay Description:Inhibition constant against human cloned isozyme (hCA IX) by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50170758(2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)-5-{3-[4-(4-sul...)
Affinity DataKi:  34nMAssay Description:Inhibition constant against human (cloned) isozyme (hCA II) by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50170758(2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)-5-{3-[4-(4-sul...)
Affinity DataKi:  630nMAssay Description:Inhibition constant against human (cloned) isozyme (hCA I) by the CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed