BDBM50192829 CHEMBL3958704::US10188627, Compound 8a

SMILES CN(Cc1ccccc1OC\C=C(/C)CCC(O)=O)C(=O)c1ccc(cc1)-c1ccco1

InChI Key InChIKey=WZFMWAHUFRLQRH-XDJHFCHBSA-N

Data  1 Kd  18 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50192829   

TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Mitobridge

US Patent
LigandPNGBDBM50192829(CHEMBL3958704 | US10188627, Compound 8a)
Affinity DataEC50:  5.06nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Mitobridge

US Patent
LigandPNGBDBM50192829(CHEMBL3958704 | US10188627, Compound 8a)
Affinity DataEC50:  56nMAssay Description:Cell Handling: PathHunter NHR cell lines were expanded from freezer stocks according to standard procedures. Cells were seeded in a total volume of 2...More data for this Ligand-Target Pair
TargetPPAR delta protein(Rattus norvegicus (Rat))
Mitobridge

US Patent
LigandPNGBDBM50192829(CHEMBL3958704 | US10188627, Compound 8a)
Affinity DataEC50:  5.06nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair