BDBM50200305 (S)-1-(4-iodobenzyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)isatin::(S)-1-(4-iodobenzyl)-5-[1-(2-phenoxymethylpyrrolidinyl)sulfonyl]isatin::CHEMBL384023
SMILES Ic1ccc(CN2C(=O)C(=O)c3cc(ccc23)S(=O)(=O)N2CCC[C@H]2COc2ccccc2)cc1
InChI Key InChIKey=OOMWRPAWHLYIEI-FQEVSTJZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50200305
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-1(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of caspase 1More data for this Ligand-Target Pair
TargetCaspase-6(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of caspase 6More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataEC50: 25.3nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 25.3nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
TargetCaspase-1(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
TargetCaspase-6(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 8 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of caspase 8More data for this Ligand-Target Pair
Affinity DataIC50: 18.6nMAssay Description:Inhibition of caspase 7More data for this Ligand-Target Pair