BDBM50235980 2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid::CHEMBL429876::CILENGITIDE::EMD-12192::EMD-121974::[(2S,5R,8S,11S)-5-benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13pentaaza-cyclopentadec-2-yl]-acetic acid::c(RGDfMeV)::cyclo(Arg-Gly-Asp-D-Phe-[N-Me]Val)
SMILES [#6]-[#6](-[#6])-[#6@@H]-1-[#7](-[#6])-[#6](=O)-[#6@@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6]-1=O
InChI Key InChIKey=AMLYAMJWYAIXIA-VWNVYAMZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50235980
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£T M£Nchen
Curated by ChEMBL
Technische Universit£T M£Nchen
Curated by ChEMBL
Affinity DataIC50: 4.21E+3nMAssay Description:Inhibition of fibrinogen binding to Integrin alpha2bbeta3 receptor (unknown origin) by competitive ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of latency-associated peptide binding to Integrin alphaVbeta6 receptor (unknown origin) by competitive ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibition of vitronectin binding to Integrin alphaVbeta5 receptor (unknown origin) by competitive ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Inhibition of vitronectin binding to Integrin alphaVbeta3 receptor (unknown origin) by competitive ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of fibronectin binding to human Integrin alpha5beta1 receptor by competitive ELISAMore data for this Ligand-Target Pair