BDBM50247528 CHEMBL4099866
SMILES CN(C)c1ccc(cc1)-c1c2ccc(n2)c(-c2ccc(cc2)N(C)C)c2ccc([nH]2)c(-c2ccc(cc2)C(O)=O)c2ccc(n2)c(-c2ccc(cc2)C(O)=O)c2ccc1[nH]2
InChI Key InChIKey=ZHCCIJNKMYSLRS-DKVILZSDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50247528
Affinity DataEC50: 1.47E+3nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
Affinity DataKd: 381nMAssay Description:Binding affinity to recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells by spectrofluorimetric methodMore data for this Ligand-Target Pair
Affinity DataEC50: 381nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair