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Found 3 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 1' and Ligand = 'BDBM50247528'
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247528(CHEMBL4099866)
Affinity DataEC50:  1.47E+3nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247528(CHEMBL4099866)
Affinity DataKd:  381nMAssay Description:Binding affinity to recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247528(CHEMBL4099866)
Affinity DataEC50:  381nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed