BDBM50262188 1-(1,2,4-Oxadiazol-5-yl)-7-phenylheptan-1-one::CHEMBL448922

SMILES O=C(CCCCCCc1ccccc1)c1ncno1

InChI Key InChIKey=ZZEHRRGWKDFITC-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50262188   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262188(1-(1,2,4-Oxadiazol-5-yl)-7-phenylheptan-1-one | CH...)
Affinity DataKi:  1nMpH: 9.0Assay Description:Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50262188(1-(1,2,4-Oxadiazol-5-yl)-7-phenylheptan-1-one | CH...)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262188(1-(1,2,4-Oxadiazol-5-yl)-7-phenylheptan-1-one | CH...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262188(1-(1,2,4-Oxadiazol-5-yl)-7-phenylheptan-1-one | CH...)
Affinity DataIC50:  4nMAssay Description:Inhibition of rat FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral cholesterol ester hydrolase 1(Homo sapiens (Human))
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50262188(1-(1,2,4-Oxadiazol-5-yl)-7-phenylheptan-1-one | CH...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of KIAA1363 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed