BDBM50275735 2-(3,5-dimethoxybenzylthio)-6-methoxy-1H-benzo[d]imidazole::CHEMBL488400
SMILES COc1ccc2nc(SCc3cc(OC)cc(OC)c3)[nH]c2c1
InChI Key InChIKey=WXFIODYGMHZQAT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50275735
Affinity DataKi: 70nMAssay Description:Inhibition of recombinant CYP2C19 using 3-O-methylfluorescein as substrate preincubated for 3 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate preincubated for 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.35E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate preincubated for 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+3nMAssay Description:Agonist activity at recombinant BRS-3 receptor (unknown origin) expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.99E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using (S)-mpheytoin as substrate preincubated for 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 9.12E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin preincubated for 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair