BDBM50378857 CEFTOBIPROLE::Zeftera::Zevtera

SMILES Nc1nc(ns1)C(N=O)C(=O)N[C@H]1[C@H]2SCC(C=C3CCN([C@@H]4CCNC4)C3=O)=C(N2C1=O)C(O)=O

InChI Key InChIKey=XLHWFEHWWUCKOL-WFYGCLDHSA-N

Data  19 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50378857   

TargetPeptidase(Staphylococcus aureus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50378857(CEFTOBIPROLE | Zeftera | Zevtera)
Affinity DataIC50:  7.40E+3nMpH: 5.5Assay Description:Binding affinity to Staphylococcus aureus ATCC 433000 PBP2a by western blotting at pH 5.5 in presence of 100 uM Bocillin FLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidase(Staphylococcus aureus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50378857(CEFTOBIPROLE | Zeftera | Zevtera)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of methicillin-resistant Staphylococcus aureus COL PBP2a by competitive assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidase(Staphylococcus aureus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50378857(CEFTOBIPROLE | Zeftera | Zevtera)
Affinity DataIC50:  1.68E+3nMAssay Description:Inhibition of bocillin FL binding to methicillin-resistant Staphylococcus aureus OC 3726 penicillin-binding protein 2aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidase(Staphylococcus aureus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50378857(CEFTOBIPROLE | Zeftera | Zevtera)
Affinity DataIC50:  1.90E+3nMpH: 7.4Assay Description:Binding affinity to Staphylococcus aureus ATCC 433000 PBP2a by western blotting at pH 7.4 in presence of 100 uM Bocillin FLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed