BDBM50378857 CEFTOBIPROLE::Zeftera::Zevtera
SMILES Nc1nc(ns1)C(N=O)C(=O)N[C@H]1[C@H]2SCC(C=C3CCN([C@@H]4CCNC4)C3=O)=C(N2C1=O)C(O)=O
InChI Key InChIKey=XLHWFEHWWUCKOL-WFYGCLDHSA-N
Data 19 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50378857
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of Streptococcus pneumoniae isolate 8882 Bocillin FL binding to PBP2b 443SSNA mutantMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of Bocillin FL binding to PBP2b PBP2b 443SSNA mutant in Streptococcus pneumoniae isolate 8009 harboring E333G, N470K, E476G, T489S, E506D,...More data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 112nMAssay Description:Inhibition of Bocillin FL binding to PBP2b in laboratory-derived Streptococcus pneumoniae isolate R6More data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Bocillin FL binding to PBP2b Thr446Ala mutant in laboratory-derived Streptococcus pneumoniae isolate R6More data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: >1.49E+4nMAssay Description:Inhibition of Bocillin FL binding to PBP2b in Streptococcus pneumoniae isolate 8819 harboring E333G, I361L, E369D, S412P, N422Y, T426K, Q427L, Q438E,...More data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 3.18E+3nMAssay Description:Inhibition of Bocillin FL binding to PBP2b Thr446Ala/Ala-619-Gly mutant in laboratory-derived Streptococcus pneumoniae isolate R6More data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 112nMAssay Description:Inhibition of Bocillin FL binding to Streptococcus pneumoniae isolate 8865 PBP2bMore data for this Ligand-Target Pair