BDBM50383292 CHEMBL2029438
SMILES COc1cc(ccc1Nc1ncc2CN(Cc3ccccc3)C(=O)N(c3cccc(NC(=O)C=C)c3)c2n1)N1CCN(C)CC1
InChI Key InChIKey=JARUUYXHPLGHLF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50383292
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 0.290nMAssay Description:Inhibition of EGFR after 1.5 hr by FRET assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 1.20nMAssay Description:Binding affinity to EGFRMore data for this Ligand-Target Pair