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Found 3 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50383292'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50383292(CHEMBL2029438)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of EGFR after 1.5 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50383292(CHEMBL2029438)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50383292(CHEMBL2029438)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed