BDBM50416875 AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet

SMILES C[C@@H](NCCCc1cccc(c1)C(F)(F)F)c1cccc2ccccc12

InChI Key InChIKey=VDHAWDNDOKGFTD-MRXNPFEDSA-N

Data  3 IC50  4 EC50

PDB links: 6 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416875   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Leo Pharma

US Patent
LigandPNGBDBM50416875(AMG-073 | AMG073 HCL | CINACALCET | CINACALCET HYD...)
Affinity DataIC50:  50nMpH: 7.4 T: 2°CAssay Description:Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...More data for this Ligand-Target Pair
In DepthDetails US Patent