BDBM50428343 CHEMBL2331708
SMILES NC1=N[C@]2(C[C@H]2CCS1)c1cccc(NC(=O)c2ccc(Cl)cn2)c1
InChI Key InChIKey=WQDXYYJHDFSNIX-KZULUSFZSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50428343
Affinity DataIC50: 5nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing APP695 assessed as inhibition of amyloid beta (1 to 40) production after 18 to 20 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of BACE2 in rat INS-1E cells assessed as TMEM27 cleavage preincubated for 2 hrs followed by doxycycline addition measured after 46 hrs by ...More data for this Ligand-Target Pair