BDBM50440531 CHEMBL2426168
SMILES Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C(F)(F)F
InChI Key InChIKey=WMCOYUSJXXCHFH-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50440531
TargetRecQ-like DNA helicase BLM(Homo sapiens (Human))
Drexel University College Of Medicine
Curated by ChEMBL
Drexel University College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of BLM helicase (unknown origin) binding to DNAMore data for this Ligand-Target Pair
TargetRecQ-like DNA helicase BLM(Homo sapiens (Human))
Drexel University College Of Medicine
Curated by ChEMBL
Drexel University College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of BLM helicase (unknown origin) assessed as branch migration activityMore data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Homo sapiens (Human))
Drexel University College Of Medicine
Curated by ChEMBL
Drexel University College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of WRN helicase (unknown origin)More data for this Ligand-Target Pair
TargetRecQ-like DNA helicase BLM(Homo sapiens (Human))
Drexel University College Of Medicine
Curated by ChEMBL
Drexel University College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of His-tagged BLM (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in BLM helicase unwinding activity using...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Homo sapiens (Human))
Drexel University College Of Medicine
Curated by ChEMBL
Drexel University College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of WRN (unknown origin) by gel-based DNA unwinding assayChecked by AuthorMore data for this Ligand-Target Pair
TargetATP-dependent DNA helicase Q1(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of RECQ1 (unknown origin) by gel-based DNA unwinding assayChecked by AuthorMore data for this Ligand-Target Pair
TargetRecQ-like DNA helicase BLM(Homo sapiens (Human))
Drexel University College Of Medicine
Curated by ChEMBL
Drexel University College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.48E+4nMAssay Description:Inhibition of 5'-biotin labeled duplex forked-DNA binding to BLM (unknown origin) assessed as increase in unbound DNA levels after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetRecQ-like DNA helicase BLM(Homo sapiens (Human))
Drexel University College Of Medicine
Curated by ChEMBL
Drexel University College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of BLM (unknown origin) by gel-based DNA unwinding assayChecked by AuthorMore data for this Ligand-Target Pair