Found 5 Enz. Inhib. hit(s) with Target = 'RecQ-like DNA helicase BLM' and Ligand = 'BDBM50440531' TargetRecQ-like DNA helicase BLM(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of BLM (unknown origin) by gel-based DNA unwinding assayChecked by AuthorMore data for this Ligand-Target Pair
TargetRecQ-like DNA helicase BLM(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of His-tagged BLM (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in BLM helicase unwinding activity using...More data for this Ligand-Target Pair
TargetRecQ-like DNA helicase BLM(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of BLM helicase (unknown origin) binding to DNAMore data for this Ligand-Target Pair
TargetRecQ-like DNA helicase BLM(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 3.48E+4nMAssay Description:Inhibition of 5'-biotin labeled duplex forked-DNA binding to BLM (unknown origin) assessed as increase in unbound DNA levels after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetRecQ-like DNA helicase BLM(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of BLM helicase (unknown origin) assessed as branch migration activityMore data for this Ligand-Target Pair
