BDBM50448563 CHEMBL3127347

SMILES OC(c1ccc(cc1)N1CCN(C[C@@H]1CC1CCOCC1)S(=O)(=O)c1cccs1)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=ZIIICKIMOSZOAK-IBGZPJMESA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448563   

TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50448563(CHEMBL3127347)
Affinity DataIC50:  58nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucokinase regulatory protein(Rattus norvegicus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50448563(CHEMBL3127347)
Affinity DataEC50:  5.47E+3nMAssay Description:Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed