BDBM50463985 CHEMBL4244406
SMILES CN(CCCCCCCCN=[N+]=[N-])CCCCCNC(=O)COc1cncc(c1)C#Cc1csc(C)n1
InChI Key InChIKey=VUKQZDURBZZIME-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50463985
Affinity DataKi: 5.70E+3nMAssay Description:Displacement of [3H]MPEP from recombinant mGluR5a (unknown origin) expressed in HEK293T cell membranes co-expressing human dopamine D2 receptor after...More data for this Ligand-Target Pair
Affinity DataKi: 5.80E+3nMAssay Description:Displacement of [3H]MPEP from recombinant mGluR5 (unknown origin) expressed in HEK293T cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Antagonist activity at mGluR5 (unknown origin) expressed in HEK293T cells assessed as inhibition of L-Glu-induced MAPK phosphorylation preincubated f...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor/Metabotropic glutamate receptor 5(Homo sapiens (Human))
Ghent University
Curated by ChEMBL
Ghent University
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Antagonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as inhibition of L-Glu-induced MAPK p...More data for this Ligand-Target Pair