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Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50463985'
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463985(CHEMBL4244406)
Affinity DataKi:  5.70E+3nMAssay Description:Displacement of [3H]MPEP from recombinant mGluR5a (unknown origin) expressed in HEK293T cell membranes co-expressing human dopamine D2 receptor after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463985(CHEMBL4244406)
Affinity DataKi:  5.80E+3nMAssay Description:Displacement of [3H]MPEP from recombinant mGluR5 (unknown origin) expressed in HEK293T cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463985(CHEMBL4244406)
Affinity DataIC50:  2.60E+3nMAssay Description:Antagonist activity at mGluR5 (unknown origin) expressed in HEK293T cells assessed as inhibition of L-Glu-induced MAPK phosphorylation preincubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed