Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50463985'
Affinity DataKi: 5.70E+3nMAssay Description:Displacement of [3H]MPEP from recombinant mGluR5a (unknown origin) expressed in HEK293T cell membranes co-expressing human dopamine D2 receptor after...More data for this Ligand-Target Pair
Affinity DataKi: 5.80E+3nMAssay Description:Displacement of [3H]MPEP from recombinant mGluR5 (unknown origin) expressed in HEK293T cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Antagonist activity at mGluR5 (unknown origin) expressed in HEK293T cells assessed as inhibition of L-Glu-induced MAPK phosphorylation preincubated f...More data for this Ligand-Target Pair