BDBM50556595 CHEMBL4740154

SMILES CN(CCCn1ccc(=O)c(O)c1C)CC#C

InChI Key InChIKey=OGLKVPGPJHINGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50556595   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50556595(CHEMBL4740154)
Affinity DataIC50:  2.85E+3nMAssay Description:Inhibition of self-induced amyloid beta (1 to 42) (unknown origin) aggregation incubated for 24 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50556595(CHEMBL4740154)
Affinity DataIC50:  0.320nMAssay Description:Antagonist activity at human H3 receptor expressed in HEK293 cells centrifuged for 3 mins followed by 60 mins incubation by LANCE Ultra cAMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed