BDBM50570140 CHEMBL4863321
SMILES CN([C@@H](Cc1ccccc1)C(O)=O)C(=O)c1ccc(cc1)N(CCN1CCCC1)S(=O)(=O)c1ccc(F)cc1
InChI Key InChIKey=SESRJRLBHQWLSW-MHZLTWQESA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50570140
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
Institut Pasteur De Lille
Curated by ChEMBL
Institut Pasteur De Lille
Curated by ChEMBL
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human ERAP2 assessed as hydrolysis of KSIINFEKL to SIINFEKL measured after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Institut Pasteur De Lille
Curated by ChEMBL
Institut Pasteur De Lille
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human IRAP expressed in HEK293 cells using L-AMC as substrate preincubated for 30 mins followed by substrate addition measu...More data for this Ligand-Target Pair
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
Institut Pasteur De Lille
Curated by ChEMBL
Institut Pasteur De Lille
Curated by ChEMBL
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of recombinant ERAP2 (unknown origin) expressed in baculovirus infected Hi-5 insect cells using R-AMC as substrate preincubated for 30 min...More data for this Ligand-Target Pair