BDBM50570140 CHEMBL4863321

SMILES CN([C@@H](Cc1ccccc1)C(O)=O)C(=O)c1ccc(cc1)N(CCN1CCCC1)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=SESRJRLBHQWLSW-MHZLTWQESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50570140   

TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
Institut Pasteur De Lille

Curated by ChEMBL
LigandPNGBDBM50570140(CHEMBL4863321)
Affinity DataIC50:  9.80E+4nMAssay Description:Inhibition of human ERAP2 assessed as hydrolysis of KSIINFEKL to SIINFEKL measured after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Institut Pasteur De Lille

Curated by ChEMBL
LigandPNGBDBM50570140(CHEMBL4863321)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of recombinant human IRAP expressed in HEK293 cells using L-AMC as substrate preincubated for 30 mins followed by substrate addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
Institut Pasteur De Lille

Curated by ChEMBL
LigandPNGBDBM50570140(CHEMBL4863321)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of recombinant ERAP2 (unknown origin) expressed in baculovirus infected Hi-5 insect cells using R-AMC as substrate preincubated for 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed