BDBM50582450 CHEMBL4778540

SMILES CC(=O)N1CCc2nc(N3CCC(CC3)Oc3ccc(F)cc3F)c(N[C@@H]3CCOC3)nc2C1

InChI Key InChIKey=HSWVJQBEXRKOBZ-QGZVFWFLSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50582450   

TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50582450(CHEMBL4778540)
Affinity DataKi:  9.40nMAssay Description:Displacement of 3H-RL338 from human GPR6 expressed in T-REx-CHO-GPR6 cells assessed as inhibition constant by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50582450(CHEMBL4778540)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50582450(CHEMBL4778540)
Affinity DataEC50:  3.80E+4nMAssay Description:Inverse agonist activity at human GPR6 expressed in CHO-K1 cells assessed as modulation of cAMP level incubated for 20 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed