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Found 2 Enz. Inhib. hit(s) with Target = 'G-protein coupled receptor 6' and Ligand = 'BDBM50582450'
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50582450(CHEMBL4778540)
Affinity DataKi:  9.40nMAssay Description:Displacement of 3H-RL338 from human GPR6 expressed in T-REx-CHO-GPR6 cells assessed as inhibition constant by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50582450(CHEMBL4778540)
Affinity DataEC50:  3.80E+4nMAssay Description:Inverse agonist activity at human GPR6 expressed in CHO-K1 cells assessed as modulation of cAMP level incubated for 20 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed