BDBM635459 2-Tert-butyl-N-{5-[2-cyclopropyl-5-(morpholin- 4-yl)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-2-fluoro- 4-methylphenyl}-1,3-oxazole-5-carboxamide::US11814384, Example 304

SMILES Cc1cc(F)c(NC(=O)c2cnc(o2)C(C)(C)C)cc1-c1cc(N2CCOCC2)n2nc(nc2c1)C1CC1

InChI Key InChIKey=LSXUTFVCINKIHZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635459   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM635459(2-Tert-butyl-N-{5-[2-cyclopropyl-5-(morpholin- 4-y...)
Affinity DataIC50:  5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent