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Found 1 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM635459'
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM635459(2-Tert-butyl-N-{5-[2-cyclopropyl-5-(morpholin- 4-y...)
Affinity DataIC50:  5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent