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Found 167 with Last Name = 'freeman' and Initial = 'b'
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550593(CHEMBL4746566)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550627(CHEMBL4787152)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550593(CHEMBL4746566)
Affinity DataIC50: <0.600nMAssay Description:Inhibition of TNIK (unknown origin) in presence of 10 uM ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251744(CHEMBL481672 | endo-4-(2-(3-(4-(4-(oxazol-2-yl)phe...)
Affinity DataIC50:  1nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550624(CHEMBL4759743)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550629(CHEMBL4750540)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMisshapen-like kinase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550593(CHEMBL4746566)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of MINK (unknown origin) in presence of 10 uM ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550617(CHEMBL4781045)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550595(CHEMBL4783711)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251705(4-(2-(3-(4-(4-(oxazol-2-yl)phenoxy)phenylamino)pip...)
Affinity DataIC50:  2nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550619(CHEMBL4787142)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550628(CHEMBL4740167)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550623(CHEMBL4779507)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550600(CHEMBL4745446)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550598(CHEMBL4751017)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550597(CHEMBL4757082)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550594(CHEMBL4777705)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251627(4-((methyl(3-(4-(4-(oxazol-2-yl)phenoxy)phenylamin...)
Affinity DataIC50:  3nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251665(4-(2-(4-(4-(4-(oxazol-2-yl)phenoxy)phenylamino)pip...)
Affinity DataIC50:  3nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251397(CHEMBL480334 | endo-4-((3-(4-benzylphenylamino)-8-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550607(CHEMBL4788172)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550610(CHEMBL4800212)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550616(CHEMBL4760299)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50134771(CHEMBL3754515)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550602(CHEMBL4790042)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251805(CHEMBL481171 | endo-4-((3-(4-(4-(1H-pyrrol-1-yl)ph...)
Affinity DataIC50:  4nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50138160(CHEMBL3753424)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550618(CHEMBL4778859)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251666(4-((4-((4-(4-(oxazol-2-yl)phenoxy)phenylamino)meth...)
Affinity DataIC50:  5nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251839(CHEMBL480949 | endo-4-{3-[4-(Biphenyl-4-yloxy)-phe...)
Affinity DataIC50:  5nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251743(CHEMBL481671 | endo-4-((3-(4-(4-(oxazol-2-yl)pheno...)
Affinity DataIC50:  5nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550601(CHEMBL4780690)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550593(CHEMBL4746566)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system at physiological AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251778(CHEMBL471954 | endo-4-((3-(4-(2-fluorophenoxy)phen...)
Affinity DataIC50:  6nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251775(CHEMBL480347 | endo-4-((3-(4-(4-chlorophenoxy)phen...)
Affinity DataIC50:  6nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550593(CHEMBL4746566)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550609(CHEMBL4741486)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550630(CHEMBL4780287)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251706(4-((3-(4-(4-(oxazol-2-yl)phenoxy)phenylamino)pyrro...)
Affinity DataIC50:  7nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550608(CHEMBL4753817)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550606(CHEMBL4757382)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550599(CHEMBL4740781)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550625(CHEMBL4756318)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251838(CHEMBL481531 | endo-4-((3-(4-(4-(thiazol-2-yl)phen...)
Affinity DataIC50:  8nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550622(CHEMBL4793121)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251668(4-((methyl(4-(4-(4-(oxazol-2-yl)phenoxy)phenylamin...)
Affinity DataIC50:  9nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251840(CHEMBL481110 | endo-4-((3-(4-(benzo[d]thiazol-2-yl...)
Affinity DataIC50:  9nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550615(CHEMBL4787865)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50550604(CHEMBL4797557)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 catalytic domain (1 to 328 residues) expressed in baculovirus expression system pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251667(4-((4-(4-(4-(oxazol-2-yl)phenoxy)phenylamino)cyclo...)
Affinity DataIC50:  11nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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