TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 59nMAssay Description:Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 59nMAssay Description:Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Negative allosteric modulation activity at human recombinant mGlur2 expressed in CHO cells in presence of cAMP by chemiluminescence based assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Negative allosteric modulator activity at human recombinant mGlur2 expressed in HEK293 cells by calcium assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Negative allosteric modulation activity at human recombinant mGlur2 expressed in CHO cells in presence of cAMP by chemiluminescence based assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Negative allosteric modulation activity at human recombinant mGlur2 expressed in CHO cells in presence of cAMP by chemiluminescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIF-1 alpha in human MDA-MB-468 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIF-1 alpha in human OVCAR3 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIF-1 alpha in human PANC1 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIF-1 alpha in human MDA-MB-231 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
Affinity DataIC50: 3.82E+3nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human MDA-MB-468 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human OVCAR3 cells by Western blotting analysis in normoxia conditionMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human OVCAR3 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human MDA-MB-231 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human PANC1 cells by Western blotting analysis in normoxia conditionMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human PANC1 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human MDA-MB-231 cells by Western blotting analysis in normoxia conditionMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human MDA-MB-468 cells by Western blotting analysis in normoxia conditionMore data for this Ligand-Target Pair
Affinity DataIC50: 4.89E+3nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
Affinity DataIC50: 5.04E+3nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Food Industry Research and Development Institute
US Patent
Food Industry Research and Development Institute
US Patent
Affinity DataIC50: 1.20E+4nMAssay Description:To conduct the assays, the 250 uM monasuspiloin solution was further diluted with 10% DMSO to prepare 25 uM, and 5 uM monasuspiloin samples, and the ...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Food Industry Research and Development Institute
US Patent
Food Industry Research and Development Institute
US Patent
Affinity DataIC50: 1.60E+4nMAssay Description:To conduct the assays, the 250 uM monasuspiloin solution was further diluted with 10% DMSO to prepare 25 uM, and 5 uM monasuspiloin samples, and the ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Food Industry Research and Development Institute
US Patent
Food Industry Research and Development Institute
US Patent
Affinity DataIC50: 2.70E+4nMAssay Description:To conduct the assays, the 250 uM monasuspiloin solution was further diluted with 10% DMSO to prepare 25 uM, and 5 uM monasuspiloin samples, and the ...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Food Industry Research and Development Institute
US Patent
Food Industry Research and Development Institute
US Patent
Affinity DataIC50: 3.50E+4nMAssay Description:To conduct the assays, the 250 uM monasuspiloin solution was further diluted with 10% DMSO to prepare 25 uM, and 5 uM monasuspiloin samples, and the ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.85E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataEC50: 166nMAssay Description:Positive allosteric modulation of mGlu2 receptor (unknown origin) expressed in human Flp-In-T-REx-293 cells in presence of L-glutamate by luciferase ...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Positive allosteric modulation of mGlu2 receptor (unknown origin) expressed in human Flp-In-T-REx-293 cells in presence of L-glutamate by luciferase ...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataEC50: 11nMAssay Description:Positive allosteric modulation of mGlu2 receptor (unknown origin) expressed in human Flp-In-T-REx-293 cells in presence of L-glutamate by luciferase ...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataEC50: 8.30nMAssay Description:Positive allosteric modulation of mGlu2 receptor (unknown origin) expressed in human Flp-In-T-REx-293 cells in presence of L-glutamate by luciferase ...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataEC50: 913nMAssay Description:Positive allosteric modulation of mGlu2 receptor (unknown origin) expressed in human Flp-In-T-REx-293 cells in presence of L-glutamate by luciferase ...More data for this Ligand-Target Pair