TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataKi: 42nMAssay Description:Inhibition of [3H]-[3-Me-His2]-TRH binding to thyrotropin releasing hormone receptor of rat forebrainMore data for this Ligand-Target Pair
Affinity DataKi: 840nMAssay Description:Binding affinity of the compound towards NPFF receptor was measured by the displacement of [125I]-YLFQPQRF-NH2More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Binding affinity of the compound towards NPFF receptor was measured by the displacement of [125I]-YLFQPQRF-NH2More data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-[3-Me-His2]-TRH binding to thyrotropin releasing hormone receptor of rat forebrainMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-[3-Me-His2]-TRH binding to thyrotropin releasing hormone receptor of rat forebrainMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-[3-Me-His2]-TRH binding to thyrotropin releasing hormone receptor of rat forebrainMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-[3-Me-His2]-TRH binding to thyrotropin releasing hormone receptor of rat forebrainMore data for this Ligand-Target Pair
Affinity DataKi: 1.36E+4nMAssay Description:Binding affinity of the compound towards NPFF receptor was measured by the displacement of [125I]-YLFQPQRF-NH2More data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
University Of California San Diego
Curated by ChEMBL
University Of California San Diego
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor hSSTR4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor mSSTR3More data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor mSSTR2bMore data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor mSSTR2bMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
University Of California San Diego
Curated by ChEMBL
University Of California San Diego
Curated by ChEMBL
Affinity DataIC50: 0.770nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor hSSTR5More data for this Ligand-Target Pair
Affinity DataIC50: 0.860nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor rSSTR5More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor rSSTR5More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor rSSTR5More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor mSSTR3More data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
University Of California San Diego
Curated by ChEMBL
University Of California San Diego
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor hSSTR4More data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
University Of California San Diego
Curated by ChEMBL
University Of California San Diego
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor hSSTR5More data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
University Of California San Diego
Curated by ChEMBL
University Of California San Diego
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor hSSTR5More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor rSSTR5More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Semmelweis University
Curated by ChEMBL
Semmelweis University
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of JNK1alpha1 (unknown origin)More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor rSSTR5More data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
University Of California San Diego
Curated by ChEMBL
University Of California San Diego
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor hSSTR5More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor mSSTR2bMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor mSSTR2bMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair