Affinity DataKi: 1nMAssay Description:Displacement of [3H]R-alpha-methylistamine from human histamine H3 receptor by cell-based assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]R-alpha-methylistamine from rat histamine H3 receptor by cell-based assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]R-alpha-methylistamine from mouse histamine H3 receptor by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.390nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.440nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.607nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.840nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.890nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.920nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Antagonist activity at human NPY Y5 receptor transfected in mouse LMtk cells assessed as inhibition of neuropeptide Y-induced increase in intercellul...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human NPY Y5 receptor transfected in mouse LMtk cells assessed as inhibition of neuropeptide Y-induced increase in intercellul...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human NPY Y5 receptor transfected in mouse LMtk cells assessed as inhibition of neuropeptide Y-induced increase in intercellul...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of rat Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at human NPY Y5 receptor transfected in mouse LMtk cells assessed as inhibition of neuropeptide Y-induced increase in intercellul...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of rat Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of rat Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of rat Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair