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Found 535 with Last Name = 'borges' and Initial = 'f'
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50453020(CHEMBL4209203)
Affinity DataKi:  0.310nMAssay Description:Mixed-type inhibition of recombinant human MAO-B expressed in Pichia pastoris using benzylamine as substrate by fluorimetric horseradish peroxidase-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50453020(CHEMBL4209203)
Affinity DataKi:  0.670nMAssay Description:Non-competitive inhibition of human microsomal MAO-B expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50453019(CHEMBL4206812)
Affinity DataKi:  0.790nMAssay Description:Competitive inhibition of human microsomal MAO-B expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM23556(3-Carboxamide-coumarin deriv., 32 | N-(3-chlorophe...)
Affinity DataKi:  1.20nMAssay Description:Noncompetitive inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50258188(CHEMBL4060916)
Affinity DataKi:  2.70nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50453019(CHEMBL4206812)
Affinity DataKi:  7.5nMAssay Description:Non-competitive inhibition of recombinant human MAO-B expressed in Pichia pastoris using benzylamine as substrate by fluorimetric horseradish peroxid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50086170((4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-di...)
Affinity DataKi:  10.4nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataKi:  16nMAssay Description:Inhibition of electric eel AChE assessed as inhibition constant using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50453019(CHEMBL4206812)
Affinity DataKi:  17nMAssay Description:Tight-binding competitive inhibition of recombinant human MAO-B expressed in Pichia pastoris using benzylamine as substrate by fluorimetric horseradi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50504743(CHEMBL4464272)
Affinity DataKi:  21nMAssay Description:Competitive inhibition of human microsomal MAO-B expressed in baculovirus infected BTI-TN-5B1-4 cells assessed as inhibition constant using kynuramin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50453026(CHEMBL4204513)
Affinity DataKi:  27nMAssay Description:Tight-binding competitive inhibition of recombinant human MAO-B expressed in Pichia pastoris using benzylamine as substrate by fluorimetric horseradi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50453018(CHEMBL4203592)
Affinity DataKi:  31nMAssay Description:Tight-binding competitive inhibition of recombinant human MAO-B expressed in Pichia pastoris using benzylamine as substrate by fluorimetric horseradi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50504739(CHEMBL4585553)
Affinity DataKi:  44nMAssay Description:Competitive inhibition of human microsomal MAO-B expressed in baculovirus infected BTI-TN-5B1-4 cells assessed as inhibition constant using kynuramin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50453020(CHEMBL4209203)
Affinity DataKi:  55nMAssay Description:Tight-binding competitive inhibition of recombinant human MAO-B expressed in Pichia pastoris using benzylamine as substrate by fluorimetric horseradi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50467507(CHEMBL4292235)
Affinity DataKi:  57nMAssay Description:Reversible competitive inhibition of human recombinant microsomal MAOA expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50504740(CHEMBL4514572)
Affinity DataKi:  75nMAssay Description:Competitive inhibition of human microsomal MAO-B expressed in baculovirus infected BTI-TN-5B1-4 cells assessed as inhibition constant using kynuramin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50467507(CHEMBL4292235)
Affinity DataKi:  190nMAssay Description:Mixed type inhibition of human AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured after 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519753(CHEMBL4526845)
Affinity DataKi:  258nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50467518(CHEMBL4286556)
Affinity DataKi:  337nMAssay Description:Reversible competitive inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50467507(CHEMBL4292235)
Affinity DataKi:  478nMAssay Description:Reversible competitive inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50350114(CHEMBL1814066)
Affinity DataKi:  1.35E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM82053(8-(2-Furyl)theophylline | US9138393, Theophylline ...)
Affinity DataKi:  1.71E+3nMAssay Description:Displacement of [3H]NECA from human adenosine receptor A2A expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519760(CHEMBL3950921)
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine receptor A1 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50350111(CHEMBL1814064)
Affinity DataKi:  2.89E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50453017(CHEMBL4215788)
Affinity DataKi:  2.93E+3nMAssay Description:Tight-binding competitive inhibition of recombinant human MAO-B expressed in Pichia pastoris using benzylamine as substrate by fluorimetric horseradi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM95955(MLS000693557 | N-(2-ketochromen-3-yl)benzamide | N...)
Affinity DataKi:  3.24E+3nMAssay Description:The radioligands used were 1 nM (2R,3R,4S,5R)-2-(2-chloro-6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-3,4-diol ([3H]CCPA) for hA1, 10 n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519760(CHEMBL3950921)
Affinity DataKi:  3.85E+3nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519762(CHEMBL4565447)
Affinity DataKi:  3.93E+3nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50344059(8-Hydroxy-3-phenylcoumarin | CHEMBL1777846)
Affinity DataKi:  4.62E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine receptor A1 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519754(CHEMBL1417172)
Affinity DataKi:  5.06E+3nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50344059(8-Hydroxy-3-phenylcoumarin | CHEMBL1777846)
Affinity DataKi:  5.09E+3nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519767(CHEMBL4551749)
Affinity DataKi:  5.17E+3nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM152531(N-(Coumarin-3-yl)furan-2-carboxamide (8))
Affinity DataKi:  5.18E+3nMAssay Description:The radioligands used were 1 nM (2R,3R,4S,5R)-2-(2-chloro-6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-3,4-diol ([3H]CCPA) for hA1, 10 n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50524422(CHEMBL4557635)
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of electric eel AChE assessed as inhibition constant using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50344057(8-Ethoxy-3-(4'-methoxyphenyl)coumarin | CHEMBL1777...)
Affinity DataKi:  5.32E+3nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50350112(CHEMBL1814065)
Affinity DataKi:  5.82E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519768(CHEMBL4543278)
Affinity DataKi:  6.14E+3nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519769(CHEMBL3914193)
Affinity DataKi:  6.20E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine receptor A1 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519770(CHEMBL3939546)
Affinity DataKi:  6.28E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine receptor A1 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50350118(CHEMBL1814067)
Affinity DataKi:  6.39E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM82053(8-(2-Furyl)theophylline | US9138393, Theophylline ...)
Affinity DataKi:  6.77E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine receptor A1 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519766(CHEMBL4452834)
Affinity DataKi:  6.86E+3nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519766(CHEMBL4452834)
Affinity DataKi:  6.93E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine receptor A1 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519748(CHEMBL4471897)
Affinity DataKi:  7.06E+3nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519772(CHEMBL4532465)
Affinity DataKi:  8.02E+3nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519770(CHEMBL3939546)
Affinity DataKi:  8.50E+3nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50333651(4-oxo-N-phenyl-4H-chromene-3-carboxamide | CHEMBL1...)
Affinity DataKi:  8.51E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519767(CHEMBL4551749)
Affinity DataKi:  8.56E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine receptor A1 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM152526(N-(Coumarin-3-yl)acrylamide (2))
Affinity DataKi:  8.95E+3nMAssay Description:The radioligands used were 1 nM (2R,3R,4S,5R)-2-(2-chloro-6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-3,4-diol ([3H]CCPA) for hA1, 10 n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM50519764(CHEMBL4537667)
Affinity DataKi:  9.05E+3nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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