Affinity DataKi: 0.0400nMAssay Description:Tested for the binding affinity against thrombinChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0420nMAssay Description:Inhibition of Coagulation factor IIMore data for this Ligand-Target Pair
Affinity DataKi: 0.0450nMAssay Description:Tested for selectivity against trypsinChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0450nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity towards vitronectin receptor (AlphaV-beta3 integrin).More data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.290nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.310nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.390nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.390nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity towards vitronectin receptor (AlphaV-beta3 integrin).More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -52.6kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.520nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.550nMAssay Description:Ability to displace [3H](+)-pentazocine at sigma receptor in guinea pig brain membrane was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
Affinity DataKi: 0.620nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Affinity for alphaIIb-beta3 integrinMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:Binding affinity against Coagulation factor X from rabbit purified enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.860nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Binding affinity against Coagulation factor X from rabbit purified enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.920nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair