TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Nucleic Acid Research Institute
Curated by ChEMBL
Nucleic Acid Research Institute
Curated by ChEMBL
Affinity DataKi: <5.00E+3nMAssay Description:Inhibitory activity against purine nucleoside phosphorylase (PNPase )More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Nucleic Acid Research Institute
Curated by ChEMBL
Nucleic Acid Research Institute
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Inhibitory activity against purine nucleoside phosphorylase (PNPase )More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Nucleic Acid Research Institute
Curated by ChEMBL
Nucleic Acid Research Institute
Curated by ChEMBL
Affinity DataKi: 2.00E+4nMAssay Description:Inhibitory activity against purine nucleoside phosphorylase (PNPase )More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Nucleic Acid Research Institute
Curated by ChEMBL
Nucleic Acid Research Institute
Curated by ChEMBL
Affinity DataKi: 3.00E+4nMAssay Description:Inhibitory activity against purine nucleoside phosphorylase (PNPase )More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Nucleic Acid Research Institute
Curated by ChEMBL
Nucleic Acid Research Institute
Curated by ChEMBL
Affinity DataKi: 8.00E+4nMAssay Description:Inhibitory activity against purine nucleoside phosphorylase (PNPase )More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Nucleic Acid Research Institute
Curated by ChEMBL
Nucleic Acid Research Institute
Curated by ChEMBL
Affinity DataKi: 1.10E+5nMAssay Description:Inhibitory activity against purine nucleoside phosphorylase (PNPase )More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human B1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human B1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human B1 receptor by calcium influx functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human B1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human B1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human B1 receptor by calcium influx functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human B1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human B1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human B1 receptor by calcium influx functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human B1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of human B1 receptor by calcium influx functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human B1 receptor by calcium influx functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of human B1 receptor by calcium influx functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human B1 receptor by calcium influx functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of human B1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of human B1 receptor by calcium influx functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of human B1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of human B1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of human B1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of human B1 receptor by calcium influx functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of human B1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of human B1 receptor by calcium influx functional assayMore data for this Ligand-Target Pair