TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Stony Brook University
Curated by ChEMBL
Stony Brook University
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Inhibition of Staphylococcus aureus enoyl ACP reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Displacement of [125I](+/-)DOI from human 5-HT2B receptor trasfected in CHO cell membrane after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.970nMAssay Description:Displacement of [125I](+/-)DOI from human 5-HT2B receptor trasfected in CHO cell membrane after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I](+/-)DOI from human 5-HT2B receptor trasfected in CHO cell membrane after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I](+/-)DOI from human 5-HT2B receptor trasfected in CHO cell membrane after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [125I](+/-)DOI from human 5-HT2B receptor trasfected in CHO cell membrane after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 7.10nMAssay Description:Displacement of [125I](+/-)DOI from human 5-HT2B receptor trasfected in CHO cell membrane after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 9.60nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 107nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 3.06E+3nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 3.30E+3nMAssay Description:Binding affinity of the compound towards bovine trypsin was evaluated in vitroMore data for this Ligand-Target Pair
Affinity DataKi: 4.80E+3nMAssay Description:Binding affinity of the compound towards bovine trypsin was evaluated in vitroMore data for this Ligand-Target Pair
Affinity DataKi: 6.30E+3nMAssay Description:Binding affinity of the compound towards bovine trypsin was evaluated in vitroMore data for this Ligand-Target Pair
Affinity DataKi: 9.04E+3nMAssay Description:Binding affinity of the compound towards bovine trypsin was evaluated in vitroMore data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Binding affinity of the compound towards bovine trypsin was evaluated in vitroMore data for this Ligand-Target Pair
Affinity DataKi: 1.36E+4nMAssay Description:Binding affinity of the compound towards bovine trypsin was evaluated in vitroMore data for this Ligand-Target Pair
Affinity DataKi: 1.42E+4nMAssay Description:Binding affinity of the compound towards bovine trypsin was evaluated in vitroMore data for this Ligand-Target Pair
Affinity DataKi: 1.56E+4nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 1.71E+4nMAssay Description:Binding affinity of the compound towards bovine trypsin was evaluated in vitroMore data for this Ligand-Target Pair
Affinity DataKi: 3.17E+4nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 9.72E+4nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Chong Kun Dang Research Institute
Curated by ChEMBL
Chong Kun Dang Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of bovine platelet PDE5More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Chong Kun Dang Research Institute
Curated by ChEMBL
Chong Kun Dang Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of bovine platelet PDE5More data for this Ligand-Target Pair
Affinity DataIC50: 1nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Chong Kun Dang Research Institute
Curated by ChEMBL
Chong Kun Dang Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of bovine platelet PDE5More data for this Ligand-Target Pair
Affinity DataIC50: 1nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Chong Kun Dang Research Institute
Curated by ChEMBL
Chong Kun Dang Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of bovine platelet PDE5More data for this Ligand-Target Pair