Compile Data Set for Download or QSAR
maximum 50k data
Found 76 with Last Name = 'mattern' and Initial = 'mr'
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17468(1,2,3-triazole analogue, 24 | 5-(3,4-dibromophenyl...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17461(1,2,3-triazole analogue, 17 | 5-(4-iodophenyl)-1H-...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17460(1,2,3-triazole analogue, 16 | 5-(4-bromophenyl)-1H...)
Affinity DataKi:  3nM ΔG°:  -48.2kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17474(1,2,3-triazole analogue, 30 | 4-methyl-2-(1H-1,2,3...)
Affinity DataKi:  3nM ΔG°:  -48.2kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17467(1,2,3-triazole analogue, 23 | 5-(3-bromophenyl)-1H...)
Affinity DataKi:  4nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17473(1,2,3-triazole analogue, 29 | 3-methyl-2-(1H-1,2,3...)
Affinity DataKi:  6nM ΔG°:  -46.5kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17459(1,2,3-triazole analogue, 15 | 5-(4-chlorophenyl)-1...)
Affinity DataKi:  6nM ΔG°:  -46.5kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17475(1,2,3-triazole analogue, 31 | 5-methyl-2-(1H-1,2,3...)
Affinity DataKi:  8nM ΔG°:  -45.7kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17469(1,2,3-triazole analogue, 25 | 5-(1-benzofuran-2-yl...)
Affinity DataKi:  13nM ΔG°:  -44.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17447(1,2,3-triazole analogue, 3 | 5-(4-methylphenyl)-1H...)
Affinity DataKi:  15nM ΔG°:  -44.2kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17466(1,2,3-triazole analogue, 22 | 5-(3-iodophenyl)-1H-...)
Affinity DataKi:  16nM ΔG°:  -44.0kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17462(1,2,3-triazole analogue, 18 | 5-(3-methylphenyl)-1...)
Affinity DataKi:  18nM ΔG°:  -43.8kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17465(1,2,3-triazole analogue, 21 | N-benzyl-3-(1H-1,2,3...)
Affinity DataKi:  29nM ΔG°:  -42.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17455(1,2,3-triazole analogue, 11 | 5-(4-ethylphenyl)-1H...)
Affinity DataKi:  30nM ΔG°:  -42.5kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17470(1,2,3-triazole analogue, 26 | 2-(1H-1,2,3-triazol-...)
Affinity DataKi:  41nM ΔG°:  -41.7kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17449(1,2,3-triazole analogue, 5 | 1H,4H-indeno[1,2-d][1...)
Affinity DataKi:  52nM ΔG°:  -41.2kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17476(1,2,3-triazole analogue, 32 | 2-methyl-6-(1H-1,2,3...)
Affinity DataKi:  52nM ΔG°:  -41.2kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17448(1,2,3-triazole analogue, 4 | 5-phenyl-1H-1,2,3-tri...)
Affinity DataKi:  70nM ΔG°:  -40.4kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17452(1,2,3-triazole analogue, 8 | 5-(2-methylphenyl)-1H...)
Affinity DataKi:  112nM ΔG°:  -39.3kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17453(1,2,3-triazole analogue, 9 | 5-(2-methoxyphenyl)-1...)
Affinity DataKi:  150nM ΔG°:  -38.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17471(1,2,3-triazole analogue, 27 | 3-(1H-1,2,3-triazol-...)
Affinity DataKi:  260nM ΔG°:  -37.2kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17464(1,2,3-triazole analogue, 20 | 3-(1H-1,2,3-triazol-...)
Affinity DataKi:  280nM ΔG°:  -37.0kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17450(4-(4-methylphenyl)-1H-pyrazole | pyrazole analogue...)
Affinity DataKi:  280nM ΔG°:  -37.0kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17463(1,2,3-triazole analogue, 19 | 3-(1H-1,2,3-triazol-...)
Affinity DataKi:  300nM ΔG°:  -36.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17458(1,2,3-triazole analogue, 14 | 4-(1H-1,2,3-triazol-...)
Affinity DataKi:  337nM ΔG°:  -36.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17454(1,2,3-triazole analogue, 10 | 5-(2-phenylphenyl)-1...)
Affinity DataKi: >1.00E+3nM ΔG°: >-33.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17456(1,2,3-triazole analogue, 12 | 5-(4-propylphenyl)-1...)
Affinity DataKi: >1.00E+3nM ΔG°: >-33.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17457(1,2,3-triazole analogue, 13 | 4-(1H-1,2,3-triazol-...)
Affinity DataKi: >1.00E+3nM ΔG°: >-33.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17472(1,2,3-triazole analogue, 28 | 4-(1H-1,2,3-triazol-...)
Affinity DataKi: >1.00E+3nM ΔG°: >-33.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50259819(CHEMBL481635 | Calceolarioside | Calceolarioside A)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50269517(CHEMBL504363 | Forsythiaside | forsythoside A)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50478448(CHEMBL464362)
Affinity DataIC50:  2.83E+3nMAssay Description:Inhibition of human recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50478445(Dehydrohirsutanonol | Hirsutanone | Hirsutenone | ...)
Affinity DataIC50:  4.26E+3nMAssay Description:Inhibition of human recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50269516(CHEMBL518414 | Calceolarioside B)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50478446(CHEMBL464363)
Affinity DataIC50:  4.81E+3nMAssay Description:Inhibition of human recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Saccharomyces cerevisiae S288c)
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50090044((Z)-2',3'-dihydroxy-3,4,4',5-tetramethoxystilbene ...)
Affinity DataIC50:  4.81E+3nMAssay Description:Inhibition of topoisomerase 1 in Saccharomyces cerevisiae RS321N in galactose medium by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Saccharomyces cerevisiae S288c)
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50090044((Z)-2',3'-dihydroxy-3,4,4',5-tetramethoxystilbene ...)
Affinity DataIC50:  5.71E+3nMAssay Description:Inhibition of topoisomerase 1 in Saccharomyces cerevisiae RS321N in glucose medium by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50377909(ACETOSIDE)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of human recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50478447(Hirsutanonol)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of human recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50269518(CHEMBL452413 | Plantainoside D)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of human recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50478444(Oregonin)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of human recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50250350(CHEMBL450121 | Leucosceptoside A)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Saccharomyces cerevisiae S288c)
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  2.08E+4nMAssay Description:Inhibition of topoisomerase 1 in Saccharomyces cerevisiae RS321N in galactose medium by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Saccharomyces cerevisiae S288c)
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  2.33E+4nMAssay Description:Inhibition of topoisomerase 1 in Saccharomyces cerevisiae RS321N in glucose medium by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50241873(CHEMBL499145 | Poliumoside)
Affinity DataIC50:  2.44E+4nMAssay Description:Inhibition of human recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50269515(2-(3-hydroxy-4-methoxy-phenyl)-ethyl-O-(alpha-L-rh...)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of human recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Saccharomyces cerevisiae S288c)
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50478907(CHEMBL497532)
Affinity DataIC50:  1.38E+5nMAssay Description:Inhibition of topoisomerase 1 in Saccharomyces cerevisiae RS321N in galactose medium by microtiter plate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Saccharomyces cerevisiae S288c)
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM50478907(CHEMBL497532)
Affinity DataIC50: >2.01E+5nMAssay Description:Inhibition of topoisomerase 1 in Saccharomyces cerevisiae RS321N in glucose medium by microtiter plate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393440(CHEMBL2159498)
Affinity DataEC50:  8.00E+3nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393441(CHEMBL2159499)
Affinity DataEC50:  2.20E+3nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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