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Found 369 with Last Name = 'riccardi-sirtori' and Initial = 'f'
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327930(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)
Affinity DataIC50:  5nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327929(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)
Affinity DataIC50:  6nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327928(3-({[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]CARBONYL}AMI...)
Affinity DataIC50:  9nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327923(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)
Affinity DataIC50:  10nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327927(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)
Affinity DataIC50:  11nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327915(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)
Affinity DataIC50:  13nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579779(CHEMBL5091519)
Affinity DataIC50:  14nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579781(CHEMBL5094847)
Affinity DataIC50:  14nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)
Affinity DataIC50:  14nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327926(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)
Affinity DataIC50:  18nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)
Affinity DataIC50:  18nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)
Affinity DataIC50:  19nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579773(CHEMBL5079663)
Affinity DataIC50:  20nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579782(CHEMBL5078600)
Affinity DataIC50:  20nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579777(CHEMBL5090932)
Affinity DataIC50:  21nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579771(CHEMBL5077194)
Affinity DataIC50:  22nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579769(CHEMBL5075042)
Affinity DataIC50:  23nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327925(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)
Affinity DataIC50:  25nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579780(CHEMBL5089356)
Affinity DataIC50:  27nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327924(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)
Affinity DataIC50:  27nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM124951(US8765972, 4)
Affinity DataIC50:  27nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction in H2O2-induced PAR formation incubated for 30 mins followed by H2O2 addition for 15 mi...More data for this Ligand-Target Pair
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579757(CHEMBL5084844)
Affinity DataIC50:  28nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579775(CHEMBL5085262)
Affinity DataIC50:  28nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579770(CHEMBL5090132)
Affinity DataIC50:  29nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327923(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)
Affinity DataIC50:  31nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579785(CHEMBL5075110)
Affinity DataIC50:  31nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579786(CHEMBL5093152)
Affinity DataIC50:  31nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579774(CHEMBL5081222)
Affinity DataIC50:  31nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327922(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)
Affinity DataIC50:  32nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579772(CHEMBL5088776)
Affinity DataIC50:  33nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579784(CHEMBL5091201)
Affinity DataIC50:  34nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)
Affinity DataIC50:  35nMAssay Description:Inhibition of KITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM138344(US8877944, 49)
Affinity DataIC50:  40nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM138348(US8877944, 99)
Affinity DataIC50:  40nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measur...More data for this Ligand-Target Pair
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579764(CHEMBL5086885)
Affinity DataIC50:  40nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579778(CHEMBL5078057)
Affinity DataIC50:  43nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327921(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)
Affinity DataIC50:  44nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327920(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)
Affinity DataIC50:  45nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)
Affinity DataIC50:  45nMAssay Description:Inhibition of aurora BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327919(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)
Affinity DataIC50:  48nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327918(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)
Affinity DataIC50:  48nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579783(CHEMBL5088850)
Affinity DataIC50:  49nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579758(CHEMBL5085127)
Affinity DataIC50:  49nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM124950(US8765972, 3)
Affinity DataIC50:  50nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction in H2O2-induced PAR formation incubated for 30 mins followed by H2O2 addition for 15 mi...More data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327917(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)
Affinity DataIC50:  52nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327916(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)
Affinity DataIC50:  59nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine kinase alpha(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579765(CHEMBL5089748)
Affinity DataIC50:  61nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase C(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)
Affinity DataIC50:  62nMAssay Description:Inhibition of aurora CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327915(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)
Affinity DataIC50:  66nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Oncology

Curated by ChEMBL
LigandPNGBDBM50327914(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)
Affinity DataIC50:  83nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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