TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity to Trypanosoma brucei rhodesainMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris measured for 30 mins using Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris measured for 30 mins using Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Binding affinity to Cathepsin S (unknown origin) assessed as inhibition constant measured after 22 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 199nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Binding affinity to Cathepsin S (unknown origin) assessed as inhibition constant measured after 22 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 251nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 251nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 251nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 360nMAssay Description:Binding affinity to Cathepsin S (unknown origin) assessed as inhibition constant measured after 22 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 398nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 501nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Competitive inhibition of recombinant Trypanosoma cruzi cruzain by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:Competitive inhibition of recombinant Trypanosoma cruzi cruzain by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Mixed inhibition of recombinant Trypanosoma brucei rhodesain expressed in Pichia pastoris by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.21E+4nMAssay Description:Competitive inhibition of recombinant Trypanosoma cruzi cruzain in presence of varying levels of Z-phe-Arg-amidomethylcoumarin substrate by Lineweave...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured for ...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 145nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-aminomethylcoumarin as substrate measured after 5 mins by spectrofluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 800nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-aminomethylcoumarin as substrate measured after 5 mins by spectrofluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins without preincubation by f...More data for this Ligand-Target Pair