Compile Data Set for Download or QSAR
maximum 50k data
Found 115 with Last Name = 'silva' and Initial = 'eb'
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50568077(CHEMBL4865195)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to Trypanosoma brucei rhodesainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50311245((S)-4-methyl-2-phenyl-N-(5-phenyl-1-(phenylsulfony...)
Affinity DataKi:  6nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris measured for 30 mins using Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50229129(4-Methyl-piperazine-1-carboxylic acid [(S)-1-((E)-...)
Affinity DataKi:  7nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris measured for 30 mins using Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM31992(Dipeptidyl nitrile inhibitor, 25)
Affinity DataKi:  16nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50554308(CHEMBL4761511)
Affinity DataKi:  25nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50007619(CHEMBL3233083)
Affinity DataKi:  48nMAssay Description:Binding affinity to Cathepsin S (unknown origin) assessed as inhibition constant measured after 22 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50554304(CHEMBL4752430)
Affinity DataKi:  63nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50554307(CHEMBL4784502)
Affinity DataKi:  63nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50554305(CHEMBL4776795)
Affinity DataKi:  63nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50007630(CHEMBL3233095)
Affinity DataKi:  80nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50554296(CHEMBL4799785)
Affinity DataKi:  199nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50007620(CHEMBL3233084)
Affinity DataKi:  220nMAssay Description:Binding affinity to Cathepsin S (unknown origin) assessed as inhibition constant measured after 22 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50611831(CHEMBL5285296)
Affinity DataKi:  251nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM31970(Dipeptidyl nitrile inhibitor, 1)
Affinity DataKi:  251nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50502835(CHEMBL4463665)
Affinity DataKi:  251nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50007617(CHEMBL3233081)
Affinity DataKi:  360nMAssay Description:Binding affinity to Cathepsin S (unknown origin) assessed as inhibition constant measured after 22 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50611830(CHEMBL5269694)
Affinity DataKi:  398nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM20119((2S)-N-(cyanomethyl)-3-phenyl-2-(phenylformamido)p...)
Affinity DataKi:  501nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50397142(CHEMBL2172005)
Affinity DataKi:  1.26E+3nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50518231(CHEMBL597248 | GNF-Pf-4180 | MMV006169)
Affinity DataKi:  1.40E+3nMAssay Description:Competitive inhibition of recombinant Trypanosoma cruzi cruzain by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50322742(CHEMBL1173694 | N-(2-(1H-benzo[d]imidazol-2-yl)eth...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50546138(CHEMBL4793916)
Affinity DataKi:  3.00E+3nMAssay Description:Competitive inhibition of recombinant Trypanosoma cruzi cruzain by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50546136(CHEMBL531738)
Affinity DataKi:  1.00E+4nMAssay Description:Mixed inhibition of recombinant Trypanosoma brucei rhodesain expressed in Pichia pastoris by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50233289(CHEMBL1241726)
Affinity DataKi:  1.21E+4nMAssay Description:Competitive inhibition of recombinant Trypanosoma cruzi cruzain in presence of varying levels of Z-phe-Arg-amidomethylcoumarin substrate by Lineweave...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50126127(CHEMBL3628943)
Affinity DataIC50:  3nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50058809(CHEMBL3329524)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50611827(CHEMBL5275445)
Affinity DataIC50:  16nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463153(CHEMBL4247075)
Affinity DataIC50:  26nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463154(CHEMBL4251480)
Affinity DataIC50:  31nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50058806(CHEMBL3329519)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463143(CHEMBL4245127)
Affinity DataIC50:  145nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50007630(CHEMBL3233095)
Affinity DataIC50:  210nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50058805(CHEMBL3329518)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50306592(3-(4-((S)-3-methyl-2-(quinolin-6-ylmethylamino)but...)
Affinity DataIC50:  370nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50058808(CHEMBL3329521)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50:  400nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-aminomethylcoumarin as substrate measured after 5 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50058804(CHEMBL3329515)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50612895(CHEMBL5287453)
Affinity DataIC50:  450nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50007623(CHEMBL3233088)
Affinity DataIC50:  800nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50322742(CHEMBL1173694 | N-(2-(1H-benzo[d]imidazol-2-yl)eth...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50114666(5-(4-chlorophenyl)-2-furaldehyde thiosemicarbazone...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50058802(CHEMBL3329513)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50058803(CHEMBL2409542)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50007619(CHEMBL3233083)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50568076(CHEMBL4877896)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50187500(CHEMBL3828526)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-aminomethylcoumarin as substrate measured after 5 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50322743(8-chloro-N-(3-morpholinopropyl)-5H-pyrimido[5,4-b]...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50546137(CHEMBL582420 | MMV019202 | TCMDC-123752)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins without preincubation by f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 115 total ) | Next | Last >>
Jump to: