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Found 664 with Last Name = 'vogel' and Initial = 'p'
TargetTissue alpha-L-fucosidase(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50304627((2S,3S,4R,5R,6S)-6-methylpiperidine-2,3,4,5-tetrao...)
Affinity DataKi:  1nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase by para-nitrophenolate release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50065258((2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2...)
Affinity DataKi:  3nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase by para-nitrophenolate release assayMore data for this Ligand-Target Pair
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104394((4S,5R)-2-Methyl-piperidine-3,4,5-triol | CHEMBL87...)
Affinity DataKi:  5nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104394((4S,5R)-2-Methyl-piperidine-3,4,5-triol | CHEMBL87...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against alpha-L-fucosidase of bovine epididymis expressed as KiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104387((4R,5R)-6-Hydroxymethyl-2-methyl-2,3,4,5-tetrahydr...)
Affinity DataKi:  7nMAssay Description:Inhibitory activity against alpha-L-fucosidase of bovine epididymis expressed as KiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50304628((2S,3R,4S)-2-methyl-3,4-dihydro-2H-pyrrole-3,4-dio...)
Affinity DataKi:  10nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase by para-nitrophenolate release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104405(3,4-Dihydroxy-5-methyl-pyrrolidine-2-sulfonic acid...)
Affinity DataKi:  10nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104403((2R,3S)-2-Amino-5-methyl-piperidine-3,4-diol | CHE...)
Affinity DataKi:  16nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168997(4-Fluoro-benzoic acid 2-[((2R,3R,4S)-3,4-dihydroxy...)
Affinity DataKi:  19nMAssay Description:Binding affinity against alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)
Affinity DataKi:  94nMAssay Description:Inhibition of human recombinant IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition measured after 10 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM81348(β-Lapachone (A3) | Beta lapachone | R115 (Rea...)
Affinity DataKi:  100nMAssay Description:Noncompetitive inhibition of human recombinant IDO1 expressed in Escherichia coli by Michaelis-Menton nonlinear regression plot analysis in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  135nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104402(2-Methyl-3,4-dihydro-2H-pyrrole-3,4-diol | CHEMBL8...)
Affinity DataKi:  160nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104390((R)-2-((R)-2-Allyloxy-4,5-dihydroxy-6-hydroxymethy...)
Affinity DataKi:  210nMAssay Description:Inhibitory activity against alpha-L-fucosidase of bacillus species (K40T) expressed as KiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104410((2R,3R)-4-Amino-6-methyl-cyclohexane-1,2,3-triol |...)
Affinity DataKi:  230nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104399((R)-4-Benzylamino-5-methyl-cyclopentane-1,2,3-trio...)
Affinity DataKi:  680nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104395((4R,5R)-6-Hydrazino-2-methyl-2,3,4,5-tetrahydro-py...)
Affinity DataKi:  820nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50304626((2R,3S,4S,5S)-2-methylpiperidine-3,4,5-triol | CHE...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of bovine kidney alpha-L-fucosidase by para-nitrophenolate release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168999((2R,3R,4R,5R)-5-(Benzylamino-methyl)-pyrrolidine-2...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168991((2R,3S,4R,5R)-2-Hydroxymethyl-5-[((R)-2-hydroxy-1-...)
Affinity DataKi:  1.35E+3nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50403111(CHEMBL1289015)
Affinity DataKi:  1.40E+3nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50183456(CHEMBL425403 | N-methyl-N'-9-phenanthrylimidodicar...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human recombinant IDO1 expressed in yeast IS20-2B using tryptophan as substrate by methylene blue/ascorbate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104401(2-Methyl-pyrrolidine-3,4-diol | CHEMBL314405)
Affinity DataKi:  2.00E+3nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168998((2R,3R,4S)-2-((R)-Indan-1-ylaminomethyl)-pyrrolidi...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104392((6S,7R)-2-Butylamino-4,7-bis-hydroxymethyl-[1,3]di...)
Affinity DataKi:  2.80E+3nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50403938(CHEMBL2114150)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition constant (Competitive)of the compound against alpha-L-Fucosidase from Human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104397(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibitory activity against alpha-L-Fucosidase of bovine epididymis expressed as KiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104396(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Affinity DataKi:  3.20E+3nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104398((R)-2-Methyl-6-(4-nitro-phenylsulfanyl)-tetrahydro...)
Affinity DataKi:  3.30E+3nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104406(CHEMBL431802 | N-((3R,4R)-3,4,5-Trihydroxy-piperid...)
Affinity DataKi:  4.00E+3nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50279937(CHEMBL1985550)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of human recombinant IDO1 using L-tryptophan as substrate after 15 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104396(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Affinity DataKi:  4.80E+3nMAssay Description:Inhibitory activity against alpha-L-Fucosidase of human placenta expressed as KiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104386(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibitory concentration against alpha-L-Fucosidase of human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucosidase A(Caldocellum saccharolyticum)
Institut De Chimie Organique De L'Université

Curated by ChEMBL
LigandPNGBDBM50073992(((3aS,4aS,7aS,7bR)-6,6-Dimethyl-3a,4a,7a,7b-tetrah...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of beta-glucosidase from Caldocellum saccharolyticumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50403938(CHEMBL2114150)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition constant (Competitive) of the compound against alpha-l-Fucosidase from Human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104397(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibitory concentration against alpha-L-Fucosidase of bovine epididymisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50403936(CHEMBL2114148)
Affinity DataKi:  6.40E+3nMAssay Description:Inhibition constant against Beta-galactosidase from Jack beans; Mixed (Non competitive and competitive)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104389(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Affinity DataKi:  6.50E+3nMAssay Description:Inhibitory concentration against alpha-L-Fucosidase of bovine epididymisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50403936(CHEMBL2114148)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibitor concentration of the compound against alpha-L-Fucosidase from Bovine epididymisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168993((2R,3R,4S)-2-(Benzylamino-methyl)-pyrrolidine-3,4-...)
Affinity DataKi:  7.40E+3nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50104307(2-(Benzylamino-methyl)-pyrrolidine-3,4-diol | CHEM...)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibitory activity towards Alpha-mannosidase from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50075942(CHEMBL165192 | N-[2,5-Dihydroxy-6-hydroxymethyl-4-...)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition constant of the compound against beta-galactosidase enzyme of jack bean was reportedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104412((S)-5-Methyl-piperidine-3,4-diol | CHEMBL86305)
Affinity DataKi:  8.40E+3nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104386(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Affinity DataKi:  8.60E+3nMAssay Description:Inhibitory activity against alpha-L-Fucosidase of human placenta expressed as KiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50220499(CHEMBL3350284)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition constant (Competitive) against alpha-L-Fucosidase from Bovine epididymisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50403870(CHEMBL1289017)
Affinity DataKi:  9.00E+3nMAssay Description:In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104388(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibitory activity against alpha-L-Fucosidase of bovine epididymis expressed as KiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104393(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Affinity DataKi:  9.10E+3nMAssay Description:Inhibitory activity against alpha-L-Fucosidase of bovine epididymis expressed as KiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50220501(CHEMBL3350285)
Affinity DataKi:  9.10E+3nMAssay Description:Inhibition constant of the compound against Beta-galactosidase from Bovine liver; Mixed(Competitive and Non Competitive)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  9.50E+3nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from AlmondMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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