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Found 47 with Last Name = 'zachary' and Initial = 'i'
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453006(CHEMBL4217624)
Affinity DataIC50:  609nMAssay Description:Inhibition of biotinylated VEGF-A binding to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453006(CHEMBL4217624)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of biotinylated VEGF-A binding to human NRP1 expressed in human DU145 cells after 2 hrsMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313491((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...)
Affinity DataIC50:  3.00E+3nMAssay Description:Displacement of biotinylated-VEGF-A125 from human NRP1 expressed in human DU145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313491((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...)
Affinity DataIC50:  3.00E+3nMAssay Description:Displacement of biotinylated-VEGF-A125 from NRP1 b1 domain by cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313494((S)-2-[(3-{3-[(5-Chloro-1,3-dimethyl-1H-pyrazol-4-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313491((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...)
Affinity DataIC50:  7.00E+3nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in human A549 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313491((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...)
Affinity DataIC50:  8.00E+3nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313489((S)-2-{[3-(2-nitro-benzenesulfonylamino)-thiophene...)
Affinity DataIC50:  9.00E+3nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313493((S)-2-{[3-(1,2-Dimethyl-1H-imidazole-4-sulfonylami...)
Affinity DataIC50:  1.20E+4nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313484((S)-2-{[3-(4-Amino-benzenesulfonylamino)-thiophene...)
Affinity DataIC50:  1.30E+4nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313485((S)-2-{[3-(3-Amino-benzenesulfonylamino)-thiophene...)
Affinity DataIC50:  1.40E+4nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313483(CHEMBL1091089 | H-KPPR-OH)
Affinity DataIC50:  1.40E+4nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313486((S)-2-{[3-(2-Amino-benzenesulfonylamino)-thiophene...)
Affinity DataIC50:  1.70E+4nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313492((S)-2-{[3-(Benzo[1,2,5]oxadiazole-4-sulfonylamino)...)
Affinity DataIC50:  1.70E+4nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313481((2S)-2-((2S)-2-((2S)-1-((6S,12S,15S)-6-acetamido-1...)
Affinity DataIC50:  1.80E+4nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313487((S)-2-{[3-(4-Acetylamino-benzenesulfonylamino)-thi...)
Affinity DataIC50:  1.80E+4nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313491((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...)
Affinity DataIC50:  2.30E+4nMAssay Description:Displacement of biotinylated-VEGF-A125 from human NRP1 expressed in HUVECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313482(CHEMBL1090056 | H-KPAR-OH)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313490((S)-2-{[3-(2,4-Difluoro-benzenesulfonylamino)-thio...)
Affinity DataIC50:  3.30E+4nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50313488((S)-2-{[3-(4-nitro-benzenesulfonylamino)-thiophene...)
Affinity DataIC50:  5.20E+4nMAssay Description:Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453011(CHEMBL4216800)
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453012(CHEMBL4204935)
Affinity DataKd:  1.43E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453013(CHEMBL4206494)
Affinity DataKd:  3.02E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453014(CHEMBL4214846)
Affinity DataKd:  1.41E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453006(CHEMBL4217624)
Affinity DataKd:  1.32E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453015(CHEMBL4204493)
Affinity DataKd:  2.17E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453010(CHEMBL4207210)
Affinity DataKd:  76nMAssay Description:Binding affinity to recombinant human NRP1 extracellular domain by SPR methodMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453009(CHEMBL4202667)
Affinity DataKd:  1.33E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453008(CHEMBL4205347)
Affinity DataKd:  410nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453007(CHEMBL4212550)
Affinity DataKd:  1.77E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453005(CHEMBL4209362)
Affinity DataKd:  2.47E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453004(CHEMBL4205918)
Affinity DataKd:  2.44E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50452993(CHEMBL4213216)
Affinity DataKd:  1.87E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50452992(CHEMBL4218147)
Affinity DataKd:  4.52E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50452991(CHEMBL4207015)
Affinity DataKd:  1.17E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50452978(CHEMBL4218751)
Affinity DataKd:  1.86E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50452977(CHEMBL4211378)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50452976(CHEMBL4215816)
Affinity DataKd:  2.05E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50452975(CHEMBL4210862)
Affinity DataKd:  2.28E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50452974(CHEMBL4216033)
Affinity DataKd:  1.45E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50453016(CHEMBL4204363)
Affinity DataKd:  840nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50452927(CHEMBL4203943)
Affinity DataKd:  2.14E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50452926(CHEMBL4217507)
Affinity DataKd:  1.44E+4nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50452925(CHEMBL4214327)
Affinity DataKd:  1.56E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50452924(CHEMBL4209931)
Affinity DataKd:  1.38E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50452923(CHEMBL4208692)
Affinity DataKd:  680nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropilin-1(Homo sapiens (Human))
Nce Discovery (Domainex)

Curated by ChEMBL
LigandPNGBDBM50452973(CHEMBL4203815)
Affinity DataKd:  3.76E+3nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human NRP1-b1 domain expressed in Escherichia coli Rosetta Gami 2 (DE3) pLysS cells by SPR met...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed