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Found 70 with Last Name = 'zahler' and Initial = 's'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50004058((2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-yl...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)
Affinity DataIC50:  11nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50429461(CHEMBL2332369)
Affinity DataIC50:  33nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50:  50nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)
Affinity DataIC50:  63nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)
Affinity DataIC50:  66nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)
Affinity DataIC50:  72nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta3 (Gly27 to Asp718 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)
Affinity DataIC50:  88nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50429461(CHEMBL2332369)
Affinity DataIC50:  100nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50:  141nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)
Affinity DataIC50:  178nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University Of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50154564(CHEMBL3774835 | US10688093, Compound DT2012-037541...)
Affinity DataIC50:  300nMAssay Description:Inhibition of N-terminal GST-fused His6-tagged human recombinant EphB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)
Affinity DataIC50:  303nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)
Affinity DataIC50:  319nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50352019(CHEMBL1823556)
Affinity DataIC50:  350nMAssay Description:Inhibition of CDK9 by [33P]gamma-ATP incorporation assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50:  378nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50004058((2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-yl...)
Affinity DataIC50:  600nMAssay Description:Binding affinity to alpha2b/beta3 integrin (unknown origin)More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)
Affinity DataIC50:  608nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)
Affinity DataIC50:  623nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)
Affinity DataIC50:  657nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)
Affinity DataIC50:  709nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50:  806nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  900nMAssay Description:Binding affinity to alphaVbeta3 integrin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)
Affinity DataIC50:  921nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of fibronectin binding to recombinant human integrin alpha5 (Phe42 to Tyr995 residues) beta1 (Gln21 to Asp728 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University of Munich

LigandPNGBDBM7401((2 Z,3 E)-6-Bromoindirubin-3 -oxime | (3E)-6-bromo...)
Affinity DataIC50:  1.50E+3nMpH: 7.5 T: 2°CAssay Description:PDK1 protein kinase was expressed in Sf9 insect cells as human recombinant GST-fusion protein by means of the baculovirus expression systems. Protei...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)
Affinity DataIC50:  1.97E+3nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta6 (Gly22 to Asn707 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50004058((2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-yl...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of fibrinogen binding to human alpha2b/beta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545180(CHEMBL4643939)
Affinity DataIC50:  3.95E+3nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50003851((6S,12S,15S)-1,6-diamino-15-benzyl-12-(carboxymeth...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)
Affinity DataIC50:  4.86E+3nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)
Affinity DataIC50:  4.93E+3nMAssay Description:Inhibition of vitronectin binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta5 (Gly24 to Asn719 residues) expressed in CHO c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta5 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545182(CHEMBL4636873)
Affinity DataIC50:  6.88E+3nMAssay Description:Inhibition of latency-associated peptide/TGF-beta binding to recombinant human integrin alphaV (Phe31 to Val992 residues) beta8 (Glu43 to Arg684 resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Binding affinity to alpha5beta1 integrin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActin, alpha skeletal muscle(Oryctolagus cuniculus)
Ludwig-Maximilians-University

Curated by ChEMBL
LigandPNGBDBM50508923(CHEBI:49703 | LATRUNCULIN B | NSC-339663)
Affinity DataIC50:  8.47E+3nMAssay Description:Inhibition of rabbit skeletal muscle alpha-actin polymerization measured after 24 hrs in presence of ATP and fluorescent pyrene-labelled actin by flu...More data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545183(CHEMBL4648191)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545181(CHEMBL4633117)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50545184(CHEMBL4642869)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of fibrinogen binding to human platelet integrin alpha2b beta3 by ELISA based solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of fibronectin binding to human alpha5beta1 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Division Of Organic Chemistry Csir-National Chemical Laboratory (Ncl)

Curated by ChEMBL
LigandPNGBDBM50107402((S)-2-[2-((S)-2-Amino-5-carbamimidoyl-pentanoylami...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActin, alpha skeletal muscle(Oryctolagus cuniculus)
Ludwig-Maximilians-University

Curated by ChEMBL
LigandPNGBDBM50508924(CHEMBL4522174)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of rabbit skeletal muscle alpha-actin polymerization measured after 24 hrs in presence of ATP and fluorescent pyrene-labelled actin by flu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
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