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Found 439 with Last Name = 'zhai' and Initial = 'h'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307778(7-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquina...)
Affinity DataIC50:  2nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307783(CHEMBL597773 | N1-(4-(3-chloro-4-fluorophenylamino...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307768(7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307775(7-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquina...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307773(7-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquina...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307768(7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human HDAC1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307774(6-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307768(7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of human HDAC6 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307790(7-(4-(3-chloro-4-fluorophenylamino)-6-methoxyquina...)
Affinity DataIC50:  7nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307769(3-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquina...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307770(4-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquina...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307791(7-(4-(3-Ethynylphenylamino)-6-methoxyquinazolin-7-...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307768(7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of human HDAC3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307777(7-(4-(3-Chloro-4-(3-fluorobenzyloxy)phenylamino)-7...)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307771(5-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquina...)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307782(7-(4-(3-Chloro-4-fluorophenylamino)-7-(2-methoxyet...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307777(7-(4-(3-Chloro-4-(3-fluorobenzyloxy)phenylamino)-7...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  11nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307768(7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human HDAC5 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307769(3-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquina...)
Affinity DataIC50:  11nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307770(4-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquina...)
Affinity DataIC50:  12nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307768(7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human HDAC4 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307768(7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human HDAC2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307787((R)-N-Hydroxy-7-(7-methoxy-4-(1-phenylethylamino)q...)
Affinity DataIC50:  13nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307771(5-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquina...)
Affinity DataIC50:  15nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307779(7-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquina...)
Affinity DataIC50:  15nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307772(5-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307768(7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307775(7-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquina...)
Affinity DataIC50:  19nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307783(CHEMBL597773 | N1-(4-(3-chloro-4-fluorophenylamino...)
Affinity DataIC50:  20nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307773(7-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquina...)
Affinity DataIC50:  20nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307778(7-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquina...)
Affinity DataIC50:  24nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307782(7-(4-(3-Chloro-4-fluorophenylamino)-7-(2-methoxyet...)
Affinity DataIC50:  24nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307768(7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human HDAC10 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307787((R)-N-Hydroxy-7-(7-methoxy-4-(1-phenylethylamino)q...)
Affinity DataIC50:  28nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307776(7-(4-(3-Ethynyl-4-fluorophenylamino)-7-methoxyquin...)
Affinity DataIC50:  29nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307772(5-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  38nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307774(6-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  38nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307781(7-(4-(3-Chloro-4-fluorophenylamino)quinazolin-6-yl...)
Affinity DataIC50:  44nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  48nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307791(7-(4-(3-Ethynylphenylamino)-6-methoxyquinazolin-7-...)
Affinity DataIC50:  52nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307768(7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  67nMAssay Description:Inhibition of human HDAC9 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307790(7-(4-(3-chloro-4-fluorophenylamino)-6-methoxyquina...)
Affinity DataIC50:  71nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307780(7-(4-(3-Chloro-4-fluorobenzylamino)-7-methoxyquina...)
Affinity DataIC50:  72nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307776(7-(4-(3-Ethynyl-4-fluorophenylamino)-7-methoxyquin...)
Affinity DataIC50:  77nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307768(7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human HDAC8 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307781(7-(4-(3-Chloro-4-fluorophenylamino)quinazolin-6-yl...)
Affinity DataIC50:  84nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307784(7-(4-(Benzylamino)-7-methoxyquinazolin-6-yloxy)-N-...)
Affinity DataIC50:  99nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Curis

US Patent
LigandPNGBDBM279695(US10035797, Compound 34 | US10035797, Compound 37 ...)
Affinity DataIC50: <100nMAssay Description:A fluorescein isothiocyanate (FITC) labeled GM was purchase from InvivoGen (ant-fgl-1). The interaction between HSP90 and labeled GM forms the basis ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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